Clinical characteristics and outcomes in patients with acute promyelocytic leukaemia and hyperleucocytosis
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چکیده
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the past hospitalization and its association with suicide attempts and ideation in patients with mdd and comparison with bmd (depressed type) group
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Acute Promyelocytic Leukaemia
Acute promyelocytic leukemia (APL) represents 15 % of acute myeloid leukaemia. Prior to tretinoin usage, the treatment of APL was difficult and remission rates were low especially in developing countries due to mortality resulting primarily from bleeding'. APL is associated with a coagulopathy which may be due to a combination of disseminated intravascular coagulation and primary fibrinolysis. ...
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15 صفحه اولRecent advances in acute promyelocytic leukaemia
Acute promyelocytic leukaemia (APML) is a subtype of leukaemia arising from a distinct reciprocal translocation involving chromosomes 15 and 17, which results in the PML-RARA fusion gene. Over the past three decades, APML has been transformed from a highly fatal disease to a highly curable one. This drastic improvement is because of the introduction of a new treatment strategy with all-trans re...
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Young adult patients with acute lymphoblastic leukaemia (ALL) represent a unique epidemiologic subgroup in that therapy may be provided by either adult or paediatric oncologists. There seem to be no differences in presenting clinical features, immunophenotypic characteristics, or cytogenetic abnormalities for young adult ALL patients treated on paediatric or adult protocols with the exception o...
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ژورنال
عنوان ژورنال: British Journal of Haematology
سال: 2014
ISSN: 0007-1048
DOI: 10.1111/bjh.13189